پديدآورندگان :
kavosh Tehrani firoozeh Polymer Chemistry Research Laboratory, Department of Chemistry, University of Isfahan, Isfahan, 8174673441, Islamic Republic of Iran/ Polymer Technology Research Group, University of Isfahan, Isfahan, 8174673441, Islamic Republic of Iran , Koohmareh Gholam Ali Polymer Chemistry Research Laboratory, Department of Chemistry, University of Isfahan, Isfahan, 8174673441, Islamic Republic of Iran , Esmaeili Kataki Fariba Department of Plant and Animal Biology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan 8174673441, Islamic Republic of Iran , Rafiemanzelat Fatemeh Frafiemanzelat@chem.ui.ac.ir Polymer Chemistry Research Laboratory, Department of Chemistry, University of Isfahan, Isfahan,8174673441, Islamic Republic of Iran/ Polymer Technology Research Group, University of Isfahan, Isfahan, 8174673441, Islamic Republic of Iran
كليدواژه :
Biopolymer , electrospun wound dressing mat , Core , Shell nano , fibers
چكيده فارسي :
In this research we focused on the fabrication of core-shell layer configuration providing the functions of enhanced promotion of tissue regeneration . The core-shell structure composed of Collagen (Col), Chitosan (CS), AloeVera (AV), not only simulates the features of the epidermis and dermis layer of a natural skin but also benefits from the materials necessary for the regeneration of injured skin tissue during the healing process. The results of full-thickness skin wound evaluation revealed that the fabricated membrane could facilitate wound healing within 10 days.