شماره ركورد كنفرانس :
5536
عنوان مقاله :
PVA hydrogels incorporated with croboxymethyl chitosan microcapsules containing tetracycline hydrochloride: morphology and antibacterial behavior
پديدآورندگان :
Hadi zohreh Department of Chemical Engineering, University of Isfahan,P.O. Box 81746-73441, Isfahan, I.R. Iran , Navarchian Amir, H navarchian@eng.ui.ac.ir Department of Chemical Engineering, Faculty of Engineering, University of Isfahan, Isfahan, I.R. Iran
كليدواژه :
PVA , Carboxymethyl chitosan , Microcapsule , Tetracycline , HCl , Antibacterial
عنوان كنفرانس :
پانزدهمين همايش بين المللي علوم و فناوري پليمر
چكيده فارسي :
Abstract: An antibacterial polyvinyl alcohol (PVA) composite hydrogel with carboxymethyl chitosan (CMCS) microcapsules was developed for drug delivery and wound dressing application. Tetracycline hydrochloride (TCH) as an antibiotic drug is encapsulated in CMCS microcapsules (MCs). The MCs were prepared by the emulsion crosslinking method and incorporated into PVA hydrogels to produce wound dressing. MCs and PVA hydrogels were characterized by SEM and XRD. The SEM images showed average particle size of 4.7 micron for microcapsules. Antibacterial activities of hydrogels against E. coli and S.aureus demonstrated the powerful antibacterial effect of PVA/MCs wound dressing.
