شماره ركورد كنفرانس :
5536
عنوان مقاله :
Preparation and characterization of DOX delivery carrier by polymer/silica nanostructure
پديدآورندگان :
Dehghani Mahsa Nanostructures and Biopolymers Research Lab, Institute of Nanoscience and Nanotechnology, University of Kashan , Niazi Zahra Chemical Enginieering Department, Faculty of Engineering, University of Kashan , Ashjari Mohsen ashjari.m@kashanu.ac.ir Nanostructures and Biopolymers Research Lab, Institute of Nanoscience and Nanotechnology, University of Kashan/ Chemical Enginieering Department, Faculty of Engineering, University of Kashan
كليدواژه :
Biomedical , Drug Delivery , Silica , polymer
عنوان كنفرانس :
پانزدهمين همايش بين المللي علوم و فناوري پليمر
چكيده فارسي :
Considering the non-toxicity of silica particles and natural polymers as well as the suitable properties of porous materials, in this research, an attempt has been made to prepare and evaluate a hybrid nanocarrier based on silica and natural alginate polymer as an effective drug release system. In order to release the appropriate dose of doxorubicin in the target tissue, a gelatin polymer coating equipped with folate receptors has also been used, which will significantly improve the efficiency of the designed system. The chemical properties of the obtained porous silica-containing drug were addressed by FTIR analysis. This new hybrid nanocarrier can be used as a promising carrier for the treatment of cancer and controlled release of drugs.
