پديدآورندگان :
Payam Ghasem Institute of Polymeric Materials, Sahand University of Technology, Postal Code: 5331817634, New Town of Sahand, Tabriz, Iran , Behboodpour Leila Institute of Polymeric Materials, Sahand University of Technology, Postal Code: 5331817634, New Town of Sahand, Tabriz, Iran , Jalili Kiyumars k_jalili@sut.ac.ir Institute of Polymeric Materials, Sahand University of Technology, Postal Code: 5331817634, New Town of Sahand, Tabriz, Iran
كليدواژه :
Tissue engineering , Human tissue mimicking , Bio , printing , Mechanical properties.
چكيده فارسي :
Injectable biomaterials are useful for numerous biomedical applications, such as introducing therapeutics into tissues or for 3D printing. Numerous polymeric biomaterials have been developed to mimic the tissue s mechanical properties. however, designing an ideal biomaterial with tunable properties that can mimic different tissue niches remains an unfulfilled promise. Here, an injectable resilin-like elastomeric hydrogel is designed with highly tunable properties, with methacrylate polyurethane as the elastomeric part and hydroxyethyl methacrylate as the hydrogelic part (PU-HEMA). Elongation at break (λmax) and Young s module (E) can be controlled by tuning the composition of the elastomeric part. We illustrate how this prototypical polyurethane elastomer enables the replication of the mechanical properties of various tissues.
