پديدآورندگان :
Hafezi Mahshid Department of Chemical Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran , Nouri Khorasani Saied Department of Chemical Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran , Esmaeely Neisiany Rasoul Department of Materials and Polymer Engineering, Hakim Sabzevari University, Sabzevar, 9617976487, Iran , Khalili Shahla Department of Chemical Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran
كليدواژه :
Mechanical properties , GelMA , Alginate , Nano , clay , Nanocomposite IPN hydrogel
چكيده فارسي :
In the present study, a new nanocomposite interpenetrating polymer network (IPN) based on Gelatin methacrylate (GelMA)/Alginate(Alg)/Nano-clay (NC) was developed with potential application in tissue engineering. The effect of NC content on the mechanical properties of GelMA/Alg hydrogel performance was investigated via tension and compersion testings. The results confirmed the reinforcement effect of the NC on the prepared network (0, 1, 2, and 3 %wt NC content). The nanocomposite hydrogel with 2 wt % NC showed the best mechanical properties in comparison with others. The mechanical strength and tensile behaviors of GelMA/Alg/NC were determined to be ca. 165% and 105% higher than those obtained for GelMA/Alg, respectively. The results demonstrated that the prepared GelMA/Alg with 2 wt% NC has the potential to be a precursor for use as a biomaterial ink for tissue engineering applications.
