Green synthesis, optimization and antibacterial activity of silver nanoparticles using leaves extract of different weed species

Green synthesis, optimization and antibacterial activity of silver nanoparticles using leaves extract of different weed species

nanotechnology could benefit from a greener approach that promotes both performance and safety. The biomolecules found in plants induce the reduction of Ag+ ions from silver nitrate to AgNPs. The process of reduction is extra cellular and fast leading to the development of easy biosynthesis of silver nanoparticle. The green synthesis of AgNPs using plants have been reported [1, 2].Recently, there is a growing interest in the fabrication of novel AgNPs with potent antimicrobial nature. Monovalent silver compounds have been used extensively for antimicrobial treatment for decades, and recent studies suggest that the antimicrobial activity is retained in AgNPs. AgNP have a high specific area than their volume which leads to excellent antimicrobial activity as compared with bulk Ag metal [3, 4]. Considering the importance of toxicity of engineered nano- particles on physiological system, Ag-NP has been found to showhigher toxicity to microorganisms compared to human cells.The present study deals with the unreported green synthesis of AgNPs using leaves extract of some important agricultural weeds. On the basis of the available literature, we hypothesized that agricultural weeds can be utilized for the preparation of nanoparticles which shows the additional advantages of this study to make the use of agricultural waste.Several pathogenic bacteria have developed resistance against various antibiotics and the development of resistant pathogens has become a major problem. The reports on broad spectrum of antimicrobial activity have attested tremendous popularity to silver nanoparticles in therapeutic applications. In this context, the antimicrobial action of the green silver nanoparticles against drug resistant Pseudomonas aeruginosa was evaluated to show their potential property as an antibacterial agent.