Author/Authors :
Michael A. Frohman، نويسنده , , Tsung-Chang Sung، نويسنده , , Andrew J. Morris، نويسنده ,
Title Of Article :
Mammalian phospholipase D structure and regulation
Latin Abstract :
The recent identification of cDNA clones for phospholipase D1 and 2 has opened the door to new studies on its structure and regulation. PLD activity is encoded by at least two different genes that contain catalytic domains that relate their mechanism of action to phosphodiesterases. In vivo roles for PLD suggest that it may be important for multiple specialized steps in receptor dependent and constitutive processes of secretion, endocytosis, and membrane biogenesis.
NaturalLanguageKeyword :
HKD motif , Phospholipase D structure , Catalytic domain
JournalTitle :
Studia Iranica
