• Author/Authors

    Roger L. Williams، نويسنده ,

  • DocumentNumber
    1601526
  • Title Of Article

    Mammalian phosphoinositide-specific phospholipase C

  • شماره ركورد
    11767
  • Latin Abstract
    Mammalian phosphoinositide-specific phospholipases C (PI-PLCs) are involved in most receptor-mediated signal transduction pathways. The mammalian isozymes employ a modular arrangement of domains to achieve a regulated production of two key second messengers. The roles of the PH, EF hand, C2, SH2 and SH3 modules in regulation of these enzymes and in interactions with membranes and other proteins is becoming apparent from recent structural and functional studies.
  • From Page
    255
  • NaturalLanguageKeyword
    C2 domain , pH domain , phosphoinositide , phospholipase C , signal transduction
  • JournalTitle
    Studia Iranica
  • To Page
    267
  • To Page
    267