Author/Authors :
Demir, M Erzurum Bölge Eğitim ve Araştırma Hastanesi - Endokrinoloji, Turkey , Gen, R Erzurum Bölge Eğitim ve Araştırma Hastanesi - Endokrinoloji, Turkey , Hilmi, A Erzurum Bölge Eğitim ve Araştırma Hastanesi - Gastroenteroloji, Turkey
Title Of Article :
Gastric carcinoid tumours
Abstract :
Gastric carcinoid tumours are rare, but are increasing in occurence. Gastric carcinoid tumors originate from enterochromaffin-like cells. The clinical presentation is often non-specific. Three subtypes of gastric carcinoid tumors were defined. Types 1 and 2 gastric carcinoid tumours are associated with hypergastrinaemia and usually have low metastatic potential. Type 3 gastric carcinoid tumours are not associated with hypergastrinaemia and have a higher potential for metastatic disease. Most of types 1 and 2 gastric carcinoid tumors are multifocal, however type 3 gastric tumors are often solitary tumors. The development of a gastric carcinoid tumor has been responsible for many factors such as gastrin, genetic factors growth factors and matrix regulating proteins. This review will focus on clinical and pathophysiological facets of gastric carcinoid tumours, summarizing recent data on their diagnosis and management.
NaturalLanguageKeyword :
Gastric carsinoid tumors , Pathophysiology , Clinic
JournalTitle :
Ege Journal Of Medicine
