The effect of caudal levobupivacaine and morphine combination in pediatric lower extremity orthopedic surgery

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Introduction: In this study, we evaluated the peroperative and postoperative effects of caudal levobupivacaine and IV or caudal morphine retrospectively.Materials and Methods: We retrospectively evaluated the records of healthy 40 children aged between 2-12 years, who had osteotomy for lower extremity under general anesthesia and caudal blockade. The solution injected was 0.5ml.kg¹ volume of 0.25% levobupivacaine including 20μg.kg^-1morphine (Group I) or only 0.25% levobupivacaine with IV morphine added at a dose of 0.1 mg.kg^-1 (Group II). We compared the groups in terms of peroperative hemodynamic changes and postoperative analgesia.Results: No significant differences were found in terms of age, height, weight and duration of surgery. We did not observed any peroperative or postoperative hemodynamic changes needing intervention for any patients (p 0.05). The mean time to the first analgesic need was 644±160 min. for Group I and 542.3±98 min. for Group II (p 0.05). None of the patients had side effects such as motor blockade, nausea, vomiting and pruritus.Conclusion: Among pediatric patients who underwent lower extremity surgery, morphine added caudally to levobupivacaine provided a longer duration of analgesia without leading to clinically significant hemodynamic changes and side effects when compared to IV doses of morphine added to levobupivacaine.

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Caudal analgesia , morphine , levobupivacaine

Ege Journal Of Medicine

155

Ege Journal Of Medicine