The effect of PSV and MRV modes on metabolic parameters in ICU patients weaning from mechanical ventilation

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Aim: Ninety percent of patients in the ICU require mechanical ventilation. Prolonged mechanical ventilation increases mortality and morbidity. Weaning is therefore very important. The hypothesis of our study is that mandatory rate ventilation (MRV) mode has a better effect on metabolic parameters than pressure support ventilation (PSV). For this aim the oxygene expenditure (VO2), produced carbondioxide (VCO2), and Energy expenditure (EE) values were measured.Materials and Methods: Eighteen were included in the study. Basal metabolic measurements were performed with an indirect calorimetry device. Patients were randomly seperated in either PSV or MRV groups. Patients were observed for 60 minutes. Respiratory rate (RR), respiratory mechanics, VO2, VCO2, and EE values were recorded.Results: MRV group. All metabolic parameters increased in both groups after the basal measurement but there weren’t any significant difference between groups regarding percent of change. Metabolic parameters in the MRV group stabilised after the first 30 minutes, while they continued to increase in the PSV group. Conclusion: As conclusion, statistically there was no difference, but clinicaly MRV was found to produce more stabile metabolic parameters in weaning patients compared with PSV.

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Mechanical ventilation , weaning , PSV , MRV , energy expenditure

Ege Journal Of Medicine

188

Ege Journal Of Medicine