Ün, S Ergani Devlet Hastanesi - Üroloji Kliniği, Turkey , Koca, O Horasan Devlet Hastanesi - Üroloji Kliniği, Turkey , Türk, H Tepecik Eğitim Araştırma Hastanesi - Üroloji Kliniği, Turkey , Tarhan, H Tepecik Eğitim Araştırma Hastanesi - Üroloji Kliniği, Turkey , Divrik, R T Şifa Üniversitesi - Tıp Fakültesi - Üroloji Anabilim Dalı, Turkey

Results of active surveillance in low-risk localized prostate cancer patients

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Aim: To evaluate the results of active surveillance in low-risk prostate cancer patients.Materials and Methods: Patients who have been diagnosed with low-risk localized prostate cancer and accepted the active surveillance treatment option were included in the study. These patients were followed with PSA and DRE (digital rectal examination) examinations every three months and an annual 12-core prostate biopsy in our clinic. Increased risk and patient s preference determined the decision for curative treatment.Results: Data from 20 of the 45 patients under the active surveillance program and those who had at least one re-biopsy result were prospectively examined. The average follow-up period was 46 months (range 12-144 months). Six out of 20 patients (30%) were treated with curative intent. Due to an increase in Gleason score, 4 patients (20%), and 2 patients (10%), due to their own preferences, received curative treatment. Five (29.4%) of the active surveillance patients underwent curative treatment within the first year, and 1 patient (5.8%) within the second year. The mean period in undergoing treatment was 14 months.Conclusion: In low-risk patients, active surveillance ensures protection to the upmost degree from possible complications, without losing the chance of curative treatment. For this group of patients it is an acceptable alternative in terms of compliance with treatment.

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Low , risk , active surveillance , prostate cancer

Ege Journal Of Medicine

78