Author/Authors :
Cihan, S Okmeydani Training and Research Hospital - Clinic of Medical Oncology, Turkey , Atasoy, A Diyarbakir Training and Research Hospital - Clinic of Medical Oncology, Turkey , Firat, U Dicle University - Faculty of Medicine - Department of Pathology, Turkey , Komek, H Diyarbakir Training and Research Hospital - Clinic of Nuclear Medicine, Turkey , Akgul Babacan, N Cumhuriyet University - Faculty of Medicine - Department of Medical Oncology, Turkey
Abstract :
Neurofibromatosis 1 (NF1) is a neurocutaneous disorder that was known as von Recklinghausen Disease. Patients with NF1 have a propensity to develop malignant and benign nervous system tumors. There are few reported association between male breast cancer and NF1. We herein present the case of a 58-year-old male NF1 patient who presented with breast cancer. The patient is a 58-year-old male who presented with a painful mass in the right breast and back pain. Light microscopic evaluation of the biopsy from the breast mass revealed a malignant component which was considered to be invasive ductal carcinoma. Six cycles of CAF (cyclophosphamide, doxorubicin and 5-Fluorouracil) were administered every three weeks. There are a few cases in the literature about male breast cancer and NF1. Every new breast lump must be carefully examined and if necessary, further evaluation such as mammography, breast USG and breast MRI should be performed
