مرکز منطقه ای اطلاع رساني علوم و فناوري - Efficacy of metoclopramide for prevention of postoperative nausea and vomiting in dental treatment under outpatient general anesthesia

Author/Authors :

YÜKSEL, Esra Ege Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey , SERGİN, Demet Ege Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey , BALCIOĞLU, Taner Ege Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey

Abstract :

Aim: This study retrospectively evaluates the efficacy of metoclopramide in preventing postoperative nausea and vomiting (PONV) in patients who had dental treatment under outpatient general anesthesia. Materials and Methods: The records of 60 ASA I-II patients who had dental treatment under outpatient general anesthesia were examined retrospectively. From 60 patients who were included in the study, patients who receieved metoclopramide 10 mg IV after anesthesia induction comprised Group 1 (n=30) and those who did not receive any antiemetic medication comprised Group 2 (n=30). The patients were assessed in the postoperative recovery unit in terms of presence and severity of nausea/vomiting at 15, 30 min and 1, 2, 4, and 6 hour. The nausea/vomiting severity scores of the patients were measured using a 5-point scale (0=no nausea, 1=mild nausea, 2=moderate nausea, 3=vomiting less than twice an hour, 4=vomiting more than twice an hour). Additional antiemetic drug administration and side effects were recorded. Results: There were no statistically significant differences in the patients demographic data. No significant difference was found between the two groups in terms of nausea/vomiting scores at any of the postoperative measurement times (p 0.05). There was no need for additional antiemetic medications or any side effects in any of the groups. Conclusion: No significant difference was shown between the metoclopramide and control groups in terms of PONV or the need for additional antiemetic medication