Author/Authors :
Kidir, Mehtap Isparta Devlet Hastanesi - Dermatoloji Bölümü, Turkey
Title Of Article :
The relation of vitamin D with immune system, skin and cancer
Abstract :
In humans, approximately 95% of the total requirement for vitamin D is synthesized in the skin by the effects of sunlight. The active vitamin D synthesis from 25 (OH) D takes place via the 1-alpha hydroxylase enzyme both in renal and non-renal tissues. The effect of vitamin D on the receptor level is through active vitamin D. Vitamin D receptors are shown in more than 30 tissues. Non-classical effects of vitamin D are grouped under three main headings: Regulation of hormone secretion, regulation of immune function, regulation of cell proliferation and differentiation. The relationship immune system, skin diseases cancer and vitamin D is the most widely researched topics.
NaturalLanguageKeyword :
Vitamin D , immune system , skin , cancer
JournalTitle :
Medical Journal Of Suleyman Demirel University
