Önal, Süleyman Süleyman Demirel Üniversitesi - Tip Fakultesi - Mikrobiyoloji A D, Turkey , Çiftçi, Esra Süleyman Demirel Üniversitesi - Tip Fakultesi - Mikrobiyoloji A D, Turkey , Aynali, Ayse Süleyman Demirel Üniversitesi - Tip Fakultesi - Mikrobiyoloji A D, Turkey , Tola, Hasan Tahsin Istanbul Mehmet Akif Ersoy Gögüs Kalp ve Damar Cerrahisi Egitim Arastirma Hastanesi, Turkey

Assesment the specific immunoglobulin levels to the allergens of allergic children and the levels of total IgE, IgA, IgM, IgG

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Purpose: In our study, we aimed to determine allergens cause allergic reactions in the region of Elazığ. Methods: The total IgE, IgA, IgM, IgG and specific IgE levels of 77 children are represented whose ages between 2 and 12 (5.92±0.33) years and had attended with allergic complaints to the pediatric clinics of Elazig Community Hospital and Firat Medical Center of Firat University. We determined 37 were only allergic asthma, 30 were only urticaria; in 6 cases urticaria and allergic asthma were together, in 2 cases allergic rhinitis and allergic conjunctivitis were together, in one case allergic asthma and allergic dermatitis and in an other one case urticaria and allergic dermatitis were together. The total IgE and specific IgE levels in serum was measured by ELISA. Results: When we compared the IgG, IgA and IgM values (mg/dL, which are determined with the nephelometric technique) of the allergic cases with the same aged healthy ones (n:30; ages 5.53±0.26), there was no statistically significant diversity. The total IgE values (kIU/L) of the allergic cases (201.41±19.55) were statistically significantly higher than the control group (39.835±7.27) (p 0.05). Conclusions: The IgE response of the cases to the multi-allergen panel were measured and the distribution of the cases that had positive results to the panels were respectively: food panel (Fx4, n:27), house dusts panel, consists of mites and pets´ fur (HMx1, n:20), pollen panel (Bx5, n:14), animal skin addiction (Ex1, n:10), fungus panel (Mx6, n:10). The most common specific IgE to the allergens that are determined were; egg white (f1, n:35), cat epithelium (e1, n:29), caw milk (f2, n:25), dog feather (e2, n:19) and mites (d1 and d4, n:29) (International Allergen Code:IAC). The total IgG, IgA and IgM levels were assessed by the device of Beckman Array®360 Systems.

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allergen , immunoglobulin , total IgE , specific IgE

Medical Journal Of Suleyman Demirel University

87