Author/Authors :
Minareci, Edibe Akdeniz University - Medical Faculty - Departmentof Pharmacology, Turkey , Er, Arzu Akdeniz University - Medical Faculty - Department of Cardiology, Turkey , Minareci, Kenan Private Antalya Hayat Kalp Hospital, Turkey
Title Of Article :
Pharmacogenetic approach to clopidogrel resistance: recurrent stent thrombosis in two brother
Abstract :
Clopidogrel, is the antiplatelet treatment choice for prevention of thrombosis after coronary stent implantation. However, despite the use of clopidogrel, a considerable number of patients continue to have stent thrombosis. There is a growing degree of evidence that recurrence of ischemic complications may be attributed to poor response of clopidogrel. It is noteworthy to elucidate the mechanisms leading to poor clopidogrel effects. We reportrecurrent stent thrombosiswith possible clopidogrel resistanceand aimed to discuss the mechanisms of clopidogrel resistance in the light of the medical literature.
NaturalLanguageKeyword :
clopidogrel , stents , thrombosis
JournalTitle :
Medical Journal Of Suleyman Demirel University
