Author/Authors :
bardak, handan isparta özel kariyer göz hastanesi, Turkey , günay, murat zeynep kamil kadın ve çocuk hastalıkları eğitim araştırma hastanesi, Turkey , daldal, hatice dinar devlet hastanesi, Turkey , yavuz bardak, yavuz süleyman demirel üniversitesi - tıp fakültesi - göz hastalıkları anabilim dalı, Turkey
Abstract :
Purpose: To evaluate safety and effectiveness of combined intravitreal (IV) triamcinolone acetonid (TA) and IV bevacizumab (IVB) treatment in macular edema due to retinal vein occlusion in short term. Material and Methods: In this retrospective study, 20 eyes of the 20 patients with macular edema due to retinal vein occlusion 5 (25 %) patients with central retinal vein occlusion and 15 (75 %) patients with branch retinal vein occlusion) were included. Patients received combined IVTA (2 mg, 0, 05 ml) and IVB (1, 25 mg, 0, 05 ml) injection. Complete ocular examinations including corrected visual acuity (CVA), intraocular pressure (IOP), and central macular thickness (CMT) were performed. Results: The mean age of the patients (Male/Female= 11/9) was 66, 35 ± 6,002 years (mean ± standard deviation). Before combined IVTA-IVB treatment, CMT was 526,85 ± 69,20 micron. One month after combined IVTA-IVB treatment CMT was 350,65 ± 44,01 micron and 3 months after treatment CMT was 398,65 ± 58,97 micron. Before combined IVTA-IVB treatment, CVA was 1,43 ± 0,66 Log Mar. One month after combined IVTA-IVB treatment CVA was 1,025 ± 0, 61 Log Mar and 3 months after treatment CVA was 1,18 ± 0,66 Log Mar. Both CMT and CVA (in turn) base-line values decreased significantly 1 month (p=0,001, p=0,018) and 3 months (p=0,001, p=0,029) following the treatment. Conclusion: Combined IVTA-IVB treatment in macular edema due to retinal vein occlusion is safe and effective in short term.
