Author/Authors :
Durmuş, Şenay Erdoğan Erzurum Bölge Eğitim ve Araştırma Hastanesi - Patoloji Bölümü, Turkey , Özmen, Sevilay Akalp Erzurum Bölge Eğitim ve Araştırma Hastanesi - Patoloji Bölümü, Turkey , Çalık, İlknur Erzurum Bölge Eğitim ve Araştırma Hastanesi - Patoloji Bölümü, Turkey , Kurt, Ali Erzurum Bölge Eğitim ve Araştırma Hastanesi - Patoloji Bölümü, Turkey , Balta, Hilal Erzurum Bölge Eğitim ve Araştırma Hastanesi - Patoloji Bölümü, Turkey , Şener, Ebru Erzurum Bölge Eğitim ve Araştırma Hastanesi - Patoloji Bölümü, Turkey , Kabalar, Mehmet Eşref Erzurum Bölge Eğitim ve Araştırma Hastanesi - Patoloji Bölümü, Turkey , Tanrıverdi, Esra Çınar Nene Hatun Kadın Doğum Hastanesi - Jinekoloji Kliniği, Turkey
Abstract :
Aim: To assess the frequency of epithelial cell abnormalities (ECA) in Erzurum Region Training and Research Hospital population and to evaluate the control cervical smears (CS) of ASC-US (atypicall squamous cells of undetermined significance) cases. Material- Methods: 17586 CS specimens studied with liquid-based cytology and conventional techniques that came to the pathology department of our hospital during 2014 examined, retrospectively. The results were categorized according to the Bethesda system. Period of taking control CS and the results analyzed of 345 patients which diagnosed as ASCUS. Results: The age range of the patients was 20-71, the average age was 46.6±11.54. EHA was found in 413 cases (2.3%). ASC-US 1.9%, AGUS (atypical glandular cells of undetermined significance) 0.17%, ASC-H (atypical squamous cells where HSIL cannot be excluded) 0.12%, LSIL (low-grade squamous intraepithelial lesion) 0.06%, HSIL (highgrade squamous intraepithelial lesion) 0.02% were detected, respectively. In 114 out of 345 ASC-US cases control CS sampled. Control CS has taken between 0.3months (10 days)-11.2 months (mean:2.8 months). In results of control CS 104 cases (91.2%) were negative for intraepithelial lesion or malignancy and in 10 cases ECA detected. Conclusion: In the CS that examined during year 2014 in Erzurum province ECA rate was is 2.3%. This rate is higher than some provinces and regions. The mostly common diagnosis is ASC-US in ECA and the rate is 1.9%. This rate is lower than 5% that prescribed in terms of reliability of the smear test. Our squamous intraepithelial lesion (SIL) rates are relatively low but they close to literature. In 114 ASC-US cases control CS sampled and in 8.8% of them ECA detected again.
NaturalLanguageKeyword :
ASC , US , epithelial cell abnormalities , cervical smear