Author/Authors :
DOĞANTEKİN, Esin Zirve Üniversitesi - Emine-Bahaeddin Nakıboğlu Tıp Fakültesi - Tıbbi Mikrobiyoloji Anabilim Dalı, Türkiye , DOĞANTEKİN, Akif Bingöl Devlet Hastanesi - İç Hastalıkları Kliniği, Türkiye , GÜREL, Ali Fırat Üniversitesi - İç Hastalıkları Nefroloji Anabilim Dalı, Türkiye
Title Of Article :
In-Vitro Efficiency of Tigecycline on Methicillin Resistant Staphylococcus Aureus Species Isolated from Clinical Specimens
Abstract :
Objective: The major problem about staphylococal infections is methicillin resistance. Because of the fact that methicillin resistant staphilococci are also resistant to beta-lactam antibiotics, some new antibiotics are necessary that can be alternative to glucopeptides for treatment of these infections.Tigecycline a glycylcycline antibiotic is effective for treatment of many pathogen microorganisms including methicillin resistant staphylococci (MRSA). Our object in this study investigating of tigecycline effectivenes on MRSA.Material and Method: In this study we investigated tigecycline resistance in 50 clinical specimen isolated MRSA species according to CLSI criteria with minimal inhibitory concentration (MIK) method Results: MIK50 and MIK90 values of tigecycline were ,125 μg/ml and 0,5μg/ml respectively.Conclusion: Findings of this study presented that tigecycline, a new antibiotic on the market, has effective antibacterial activity on MRSA species.
NaturalLanguageKeyword :
MRSA , Tigecyclin , Minimal inhibitory concentration.
JournalTitle :
Fırat Medical Journal
