Author/Authors :
EVREN, Bahri Kahramanmaras Necip Fazıl Şehir Hastanesi - İç Hastalıkları Kliniği, Türkiye , KUTLU, Orkide Okmeydanı Eğitim ve Araştırma Hastanesi - İç Hastalıkları Kliniği, Türkiye , SAKİN, Abdullah Okmeydanı Eğitim ve Araştırma Hastanesi - Onkoloji Kliniği, Türkiye , BAŞTÜRK, Abdülkadir Konya Eğitim ve Araştırma Hastanesi - İç Hastalıkları Kliniği, Türkiye , DEMİREL, Fatma Selek Konya Eğitim ve Araştırma Hastanesi - Aile Hekimliği Kliniği, Türkiye
Abstract :
Pseudohypoparathyroidism is an autosomal dominant disorder which is characterized by unresponsiveness of target organs to the parathormone. Hypocalcemia and hyperphosphatemia are present like as hypoparathyroidism, but parathormone level is substantially high because of tissue unresponsiveness in this disorder. Pseudohypoparathyroidism type 1 is known as Albright’s hereditary osteodystrophy and is clinically recognizable in patients with characteristic round face, frontal camber, short stature, obesity, brachydactyly and mental retardation. In these patients, TSH and gonadotropin resistance may also present simultaneously. Here, we present a patient, diagnosed with Albright’s hereditary osteodystrophy and subclinical hypothyroidism that is treated successfully by calcium, vitamin D and L-thyroxin.
