Author/Authors :
ÖZGEN, Metin Fırat Üniversitesi - Tıp Fakültesi - İç Hastalıkları Anabilim Dalı, Romatoloji Bilim Dalı, TÜRKİYE , KOCA, Süleyman Serdar Fırat Üniversitesi - Tıp Fakültesi - İç Hastalıkları Anabilim Dalı, Romatoloji Bilim Dalı, TÜRKİYE
Title Of Article :
Etiopathogenesis and Current Treatment of Scleroderma
Abstract :
Scleroderma is a chronic autoimmune inflammatory disease with widespread fibrosis of the skin and internal organs. Scleroderma is characterized by vascular injury, immune activation, inflammation and fibrosis. However, controversies related with the pathogenesis of scleroderma are still existing. Moreover, scleroderma is the most unsuccessfully treated disease in the rheumatic disorders. Despite prominent advances in the treatments of scleroderma related renal crisis, interstitial lung fibrosis and pulmonary arteriel hypertension, treatment of skin involvement still continues to be a problem.
NaturalLanguageKeyword :
Scleroderma , pathogenesis , treatment
JournalTitle :
Fırat University Medical Journal Of Health Sciences
