Author/Authors :
KÖM, Mustafa Fırat Üniversitesi - Veteriner Fakültesi - Cerrahi Anabilim Dalı, Turkey
Title Of Article :
The Efficacy of Hyaluronic Acid/Carboxymethylcellulose Barriers on the Prevention of Postoperative Intraabdominal Adhesions in Rabbits
Abstract :
Intraabdominal adhesions are one of the common complications seen in abdominopelvic surgery. The purpose of this study was to assess the efficacy of hyaluronic acid/carboxymethylcellulose (HA/CMC) barriers in preventing postoperative intraabdominal adhesions in rabbits. Fourteen rabbits were used in this study. The 2x2 cm part of caecum was meticulously abraded after median laparotomy. The rabbits were divided into the control and experiment groups. No medication was given to the control group. In the experiment group; a 3x3 cm of HA/CMC barrier was covered on the abraded area. Euthenasia was performed on the 14th day postoperative. The results of macroscopic evaluation showed that adhesion scores in the experiment group were found lower than in the control group (P 0.05). Histopathologically, fibrosis and inflammation in the treatment group were lower compared to the control group (P 0.05). In conclusion; HA/CMC barriers were significantly effective in the prevention of postoperative intraabdominal adhesions in rabbits.
NaturalLanguageKeyword :
Intraabdominal adhesion , hyaluronic acid , carboxymethylcellulose , rabbit.
JournalTitle :
Fırat University Veterinary Journal Of Health Sciences
