çevik, cahide afyon kocatepe university - afyon health training school, TURKEY , ulutaş, elmas afyon kocatepe university - faculty of veterinary - department of physiology, TURKEY , demirel, hasan hüseyin afyon kocatepe university - bayat vocational school, TURKEY , ince, sinan afyon kocatepe university - faculty of veterinary - department of pharmacology and toxicology, TURKEY , eryavuz, abdullah afyon kocatepe university - faculty of veterinary - department of physiology, TURKEY

Determination of Effects on Oxidant Antioxidant Balance and Some Biochemical Parameters Consumption of Bottled, Distilled and Deionized Thermal Water in Rats

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The objective of this research is to determine the effects of the consumption of the bottled, distilled and deionized versions of thermal water taken from the Gazlıgöl district in the city of Afyonkarahisar on the oxidant – antioxidant balance and on certain biochemical parameters, along with possible effects on liver and kidney tissue. The research involved 6 rats in each group. The experiment group was given fresh, bottled, deionized and distilled thermal water for 30 days whereas the control group was given normal water. At the end of the experiment, rats’ blood samples as well as liver, kidney and heart tissue samples were taken. The research determined that the hemoglobin level in rats that consumed bottled thermal water is considerably lower than those that consumed fresh and deionized water (p 0,05). The zinc level was meaningfully lower in rats that consumed distilled water than those in the other groups (p 0,05). There was no meaningful difference among the groups in terms of the liver and kidney tissues’ MDA, GSH and SOD levels. Nevertheless, it was observed that the heart tissues’ MDA level was higher in rats that consumed bottled and deionized water than those in other groups (p 0,01) whereas the GSH and SOD levels did not change. The histopathological examination of liver and kidney tissue showed certain pathological changes.The conclusion of the research is that thermal water does not have a positive effect on the organism.

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Biochemical Parameters , Oxidant Antioxidant Balance , Thermal Water

Kocatepe Veterinary Journal

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