Author/Authors :
Sivrioglu, Ali Kemal Aksaz Military Hospital - Department of Radiology, Turkey , Basekim, Cinar Aksaz Military Hospital - Department of Radiology, Turkey , Mutlu, Hakan GATA(Gülhane Askeri Tıp Akademisi) - Haydarpasa Teaching Hospital - Department of Radiology, Turkey , Sonmez, Guner GATA (Gülhane Askeri Tıp Akademisi) - Haydarpasa Teaching Hospital - Department of Radiology, Turkey , Saglam, Muzaffer Acibadem University - Medical Faculty Hospital - Department of Radiology, Turkey , Ozturk, Ersin Acibadem University - Medical Faculty Hospital - Department of Radiology, Turkey , Ozcan, Umit Aksoy Acibadem University - School of Medicine - Department of Radiology, Turkey , Atasoy, Mehmet Mahir Acibadem University - Medical Faculty Hospital - Department of Radiology, Turkey
Abstract :
Purpose: Our aim is to determine whether there is a correlation between the histopathological diagnosis of malignant lesions with mammographic microcalciications and the characteristics of microcalciications.Materials and methods: The patients who underwent mammographic study and the pathologic correlation of malignancy were reviewed retrospectively between October 2007 and April 2011. 43 malignant lesions with microcalciications at mammography were included in the study. The types and distribution of microcalciications were assessed according to the ACR BI-RADS (American College of Radiology Breast Imaging Reporting and Data System) classiication. In the histopathological evaluation, histopathological type and nuclear grade of lesions and Ductal Carsinoma In-situ subtypes were recorded. The Spearman correlation test and cross tables were used in the statistical analysis. Results: There were no signiicance between types of microcalciications and histopathological type of lesions (p=0,124). There was no signiicant association between types of microcalciications and Ductal Carsinoma In-situ subtypes (p 0,05). Lesions that showed segmental distribution or pleomorphic microcalciications were found in association with nuclear grade 2 or 3. Pleomorphic microcalciications were seen most frequently in Invasive Ductal Carcinoma (21/26). Besides, a statistically signiicant correlation was found between the rate of in situ foci in invasive ductal cancer and the microcalciication types (p = 0,044). Since the r value was determined as -0,52, a strong inverse correlation was determined between rate of DCIS and the microcalciication types. Conclusion: The characteristics of microcalciications do not clearly indicate the histopathological type. Besides, it should be considered that spontenously resolving microcalsiications may be regarded as a malign inding.
NaturalLanguageKeyword :
Breast Neoplasm , Calciication , DCIS , Histopathology , Mammograph
