Author/Authors :
Njoya, O University of Yaounde I - Faculty of Medicine and Biomedical Sciences (FMSB) - LRH-HC, Cameroun , Njoya, O University Hospital Center (UHC) Yaoundé - Viral hepatitis clinic, Cameroun , Sosso, M Chantal Biya International Reference Center, Cameroun , Fouda, PJ Chantal Biya International Reference Center, Cameroun , Djolo, A Chantal Biya International Reference Center, Cameroun , NKam, M University Hospital Center (UHC) Yaoundé - Viral hepatitis clinic, Cameroun
Abstract :
Background: Molecular biology (MB) is an essential tool for the diagnosis and evaluation of treatment efficacy against viral hepatitis. This tool was not available in Cameroon for viral hepatitis B and C, until recently. Blood samples to be examined were systematically sent abroad via the Centre Pasteur du Cameroun (CPC). Purpose: to assess the accuracy of the results from a domestic new laboratory of MB compared to those from a laboratory abroad. Methods: We included in the study, 15 subjects randomly selected from the queue of patients followed at viral hepatitis clinic of the Yaoundé University Hospital Center. They were all carriers of chronic hepatitis C. Two blood samples of the same volume were sent the CPC and to a new MB laboratory at the Chantal Biya International Research Center (CIRCB). Neither the CPC nor the CIRCB were aware of the study. One of the two tests was free for all patients. To be acceptable to the result from the CIRCB should be the same from the outside or with than 12 IU / ml above. Results: We did not observe any significant differences from the results issued by the laboratories. Conclusion: These first results from a domestic MB laboratory are encouraging. One should promote Molecular biology should hence be promoted.
