Türk, Nilay Şen Pamukkale Üniversitesi - Tıp Fakültesi - Patoloji AD, Turkey , Demirkan, Neşe Çallı Pamukkale Üniversitesi - Tıp Fakültesi - Patoloji AD, Turkey , Taşlı, Levent Pamukkale Üniversitesi - Tıp Fakültesi - Dermatoloji AD, Turkey , Yıldız, Necibe Pamukkale Üniversitesi - Tıp Fakültesi - Dermatoloji AD, Turkey

Intravascular histiocytosis associated with rheumatoid arthritis

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Various dermatoses associated with rheumatoid arthritis (RA). have been described Recently, a specific skin lesion termed “intravascular histiocytosis” has been proposed as a new entity among these dermatoses. We report a 58-year-old man with an 8-years history of RA who presented with numerous variable sized erythematous papules, plaques and nodules on the V region of the neck, right femoral region and bilateral shins. Histopathological examination of these lesions demonstrated intraluminal aggregates mainly composed of CD68-positive histiocytes in markedly dilated vessels. In addition, after 6 months of follow-up, the patient was diagnosed as Kaposi sarcoma (KS) for another skin lesion. We discuss the pathogenesis of this association and compare with other cases reported in the literature.

92

Histiocytosis , Rheumatoid Arthritis

Pamukkale Medical Journal

95