Yüksel, Selçuk Pamukkale Üniversitesi - Tıp Fakültesi - Çocuk Nefroloji Bölümü, Turkey , Elçi, Hazal Tancer Pamukkale Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları AD, Turkey , Koçyiğit, Ali Pamukkale Üniversitesi - Tıp Fakültesi - Radyoloji Ana Bilim Dalı, Turkey , Deniz, Melis Pamukkale Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları AD, Turkey , Becerir, Tülay Pamukkale Üniversitesi - Tıp Fakültesi - Çocuk Nefroloji Bölümü, Turkey , Evrengül, Havva Pamukkale Üniversitesi - Tıp Fakültesi - Çocuk Nefroloji Bölümü, Turkey

Metabolic risk factors in children with urolithiasis: Single centre experience in southwest Turkey

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Purpose:To investigate the demographic characteristics, clinical features, and metabolic risk factors of children with urolithiasis. Materials and methods:This retrospective study included 98 patients (48 boys, 50 girls) with urolithiasis diagnosed by ultrasonography. The mean age at presentation was 59.8 (1-192) months, and the mean followup period was 5.5 (1-27) months. Clinical and laboratory data including gender, age at diagnosis, presence of family history of renal stone, follow-up duration, presenting symptoms, the history of urinary tract infection (UTI), stone localization, presence of anatomical abnormalities of the urinary tract, presence of microscopic or macroscopic hematuria, pyuria, urinary metabolic examinations, blood tests, analysis of stone composition, treatment modality, and prognosis were assessed. Results: The most common symptom was restlessness in infants ( 1year) and abdominal or flank pain in older children. Microcalculi (stone diameter 3mm) and calculi ( 3mm) were found in 29.6% and in 70.4% of the patients, respectively. Hypercalciuria was the most common abnormality, followed by hypomagnesiuria. Nearly half of the hypercalciuria cases were 1 year old. Recurrent urinary tract infection was detected in half of the patients. Four patients underwent extracorporeal shock-wave lithotripsy, four underwent open surgery, and the other 90 were treated with conservative treatment. Spontaneous passage occurred in 17 patients. Stone analysis revealed calcium-oxalate in 82.4% of the 17patients. At the time of their last visit, 70% of the patients that were treated with conservative treatment, either had stones that disappeared or diminished in size with appropriate therapy. Conclusion: In terms of stones disappearance or decrease in the size of the stones, it seems that children younger than 1 year have more disadvantages than older children. Microcalculi in children should be taken into consideration because we found that 3/5 of these cases had urinary metabolic abnormalities.

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Cystinuria , Hypercalciuria , Hyperuricosuria , Hypomagnesiuria , Microcalculi.

Pamukkale Medical Journal

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