Gürses, Merve Pamukkale Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları ABD, Denizli , Özdemi, Özmert Muhammet Ali Pamukkale Üniversitesi - Tıp Fakültesi - Neonatoloji BD, Denizli , Ergin, Hacer Pamukkale Üniversitesi - Tıp Fakültesi - Neonatoloji BD, Denizli , Küçüktaşçı, Kazım Pamukkale Üniversitesi - Tıp Fakültesi - Neonatoloji BD, Denizli , Ürey, Turgut Pamukkale Üniversitesi - Tıp Fakültesi - Neonatoloji BD, Denizli

Evaluation of the cases with lower respiratory tract infection caused by respiratory syncytial virus in our neonatal intensive care unit

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Purpose: Although respiratory syncytial virus (RSV) is a frequent agent in upper respiratory tract infections in children and adults, it usually causes lower respiratory tract infections (LRTI) such as bronchiolitis or pneumonia in newborns and infants. Chronic lung disease, congenital heart disease and premature birth are important risk factors for severe RSV infection. In this study, newborns hospitalized and treated in neonatal intensive care unit (NICU) due to LRTI and who had an identified infection with RSV were retrospectively evaluated and discussed with literature.Materials and methods: In this study, demographic and clinical characteristics of newborns admitted in NICU because of LRTI due to RSV infection between February-March 2014 were evaluated. The presence of RSV was investigated with the method of PCR in nasopharyngeal swab specimens of the cases, and the results were compared with clinical and laboratory data.Results: Seven of eleven patients with nasopharyngeal swab specimens were detected RSV-A positive in the respiratory panel, and among these, a rhinovirus concurrence was detected in one patient, and a coronavirus concurrence was detected in another patient. One of the other four cases showed only adenovirus positivity, one patient was detected only coronavirus and the remaining two patients had normal respiratory panel. Three of the RSV-A positive patients were premature and two of them had congenital heart disease. In these cases with the clinical symptoms of LRTI, 28.5% of co-infection was detected. After appropriate hydration and oxygenation,they were discharged with healing in a short time and followed as an outpatient.Conclusion: RSV infection is an important cause of LRTI in both preterm and term newborns. Although patients with premature birth and congenital heart disease show more severe clinical course, they can be successfully treated with early diagnosis and appropriate therapy.

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Lower respiratory tract infection , respiratory syncytial virus , newborn

Pamukkale Medical Journal

6

110

2016