Kozanoğlu, Banu Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey , Sezgin, Gülay Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey , Bagır, Emine Çukurova University - Faculty of Medicine - Department of Pathology, Turkey , Özkan, Ayse Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey , Bayram, İbrahim Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey , Tanyeli, Atila Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey , Küpeli, Serhan Çukurova University - Faculty of Medicine - Department of Pediatric Oncology, Pediatric Bone Marrow Transplantation Unit, Turkey

Secondary Lymphoma in a Patient with a History of Unilateral Retinoblastoma

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Second malignancies develop with increased incidence in patients with herediter retinoblastoma. The most common second malignancies in retinoblastoma survivors are soft tissue sarcoma and osteosarcoma. Lymphoma developing as a second malignancy has rarely been reported. Here we report a case of lymphoma diagnosed in a 13 year-old-boy, 12 years after the diagnosis of unilateral retinoblastoma having heterozygous p.R552 (c.1654C T) mutation, treated with enucleation and radiotherapy. The risk of second tumour is higher in the hereditary retinoblastoma, especially in cases undergoing external beam radiation therapy.

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lymphoma , retinoblastoma , second neoplasm , children

Cukurova Medical Journal

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