Author/Authors :
Kömür, Süheyla Çukurova Üniversitesi - Enfeksiyon Hastalıkları Anabilim Dalı, Turkey , Ulu, Aslıhan Çukurova Üniversitesi - Enfeksiyon Hastalıkları Anabilim Dalı, Turkey , Kurtaran, Behice Çukurova Üniversitesi - Enfeksiyon Hastalıkları Anabilim Dalı, Turkey , İnal, Ayşe Seza Çukurova Üniversitesi - Enfeksiyon Hastalıkları Anabilim Dalı, Turkey , Kuşçu, Ferit Çukurova Üniversitesi - Enfeksiyon Hastalıkları Anabilim Dalı, Turkey , Tekin, Deniz Çukurova Aşkım Tüfekçi Devlet Hastanesi - Enfeksiyon Hastalıkları Anabilim Dalı, Turkey , Taşova, Yeşim Çukurova Üniversitesi - Enfeksiyon Hastalıkları Anabilim Dalı, Turkey
Abstract :
Daptomycin is the first member of cyclic lipopeptides came into use in the treatment of resistant gram-positive infections. It is shown to be a good option in the treatment of serious infections caused by gram-positive bacteria. Eosinophilic pneumonia may occur rarely during the use of daptomycin. In this paper we described 5 cases of daptomycin-associated eosinophilic pneumonia. Sudden onset of respiratory failure with tachypnea, tachycardia was observed, peripheral eosinophilia was detected in one patient. The symptoms usually resolved with supportive treatment and after discontinuation of the drug, but steroid treatment and mechanical ventilation was required in some patients. Eosinophilic pneumonia in the sudden onset of respiratory failure should be kept in mind during daptomycin treatment.
