مرکز منطقه ای اطلاع رساني علوم و فناوري - Early and mid-term results of the arterial switch operation: a 7-year, single-center experience

Abstract :

Purpose: The aim of this paper was to describe the outcomes in patients submitted to arterial switch operation and to analyze the predictors of in-hospital mortality and further need of re- operation at a single-center institution. We reviewed our 7-year experience with arterial switch operation (ASO) for transposition of the great arteries (TGA) or Taussig-Bing anomaly (TBA) to assess the early and mid-term outcomes. Material and Methods: Between January 2009 and May 2016, 34 consecutive patients who underwent ASO for TGA with IVS (intact ventricular septum), TGA with VSD (ventricular septal defect) and Taussing bing anomaly were included in this retrospective study. The patients performed by same surgeons .Patients charts, surgical reports and echocardiograms were retrospectively reviewed. Median follow-up time was ranged from 1 to 7 years, 42.2 (0.4-84) months. Results: There were 2 (5.9 %) in-hospital deaths. Late deaths occurred in 1 ( 2.9 %) of 31 survivors. One patient (2.9 %) required reintervention. The freedom from reintervention rate was 97.0 % at 7 years respectively. Two patients (5.9 %) had developed moderate neo-aortic regurgitation during the follow-up and one patient underwent reoperation mainly for neo-pulmonary artery stenosis. The analysis showed that weight, cross clamp (CC) time, cardiopulmonary bypass (CPB) time, age of operation are the strong predictors for mortality. Conclusion: ASO is a procedure performed for the treatment of various forms of TGA with acceptable early and midterm outcomes.ASO also can be performed with a low risk of early mortality and satisfactory mid-term outcomes even in a small volume center.