Author/Authors :
KUKUL GÜVEN, Fatma Mutlu Cumhuriyet Üniversitesi - Tıp Fakültesi - Acil Tıp Anabilim Dalı, Turkey , TÜRKDOĞAN, Kenan Ahmet Cumhuriyet Üniversitesi - Tıp Fakültesi - Acil Tıp Anabilim Dalı, Turkey , Hakan EREN, Şevki Cumhuriyet Üniversitesi - Tıp Fakültesi - Acil Tıp Anabilim Dalı, Turkey , AYDIN, Hüseyin Cumhuriyet Üniversitesi - Tıp Fakültesi - Biyokimya Anabilim Dalı, Turkey , KORKMAZ, İlhan Cumhuriyet Üniversitesi - Tıp Fakültesi - Acil Tıp Anabilim Dalı, Turkey , COŞKUN, Abuzer Cumhuriyet Üniversitesi - Numune Hastanesi - Acil Servis, Turkey
Abstract :
Methanol is a very poisonous substance that is used as an industrial solvent and automotive antifreeze. Toxic dose is between 20-250 ml and causes neurological symptoms such as headache, cerebral edema and putamen necrosis within the first 12 to 14 hours. Central nervous system and visual cortex are the main areas which are damaged by methanol poisoning. Methyl alcohol is not toxic until its toxic metabolites turn into formic acid. Formic acid is especially responsible for the clinical findings. Serum half-life of methanol is 14 to 20 hours in mild and 24 to 30 hours in severe toxicity. Gastric lavage, fomepizole, ethanol and hemodialysis are used in the treatment. In this study, we aimed to review and discuss information from literature about the treatment and monitoring of methanol poisoning in three cases followed at emergency department.
NaturalLanguageKeyword :
Methanol poisoning , emergency , blurred vision , hemodialysis
