Author/Authors :
KUTLU, Orkide Okmeydani Training and Research Hospital - Department of Internal Medicine, Turkey , LARSEN, Caecilie Crawley University of Chicago - Department of Medicine, USA , GREENBERG, Solomon Maximo University of Chicago - Department of Medicine, USA , FERRARA, Alfonso Massimiliano University of Chicago - Department of Medicine, USA , BURNIK, Ferda Sevimli Konya Training and Research Hospital - Department of Internal Medicine, Division of Endocrinology and Metabolism, Turkey , ECİRLİ, Samil Konya Training and Research Hospital - Department of Internal Medicine, Division of Endocrinology and Metabolism, Turkey , REFETOFF, Samuel University of Chicago - Department of Medicine, USA , DURAN, Cevdet Konya Training and Research Hospital - Department of Internal Medicine, Division of Endocrinology and Metabolism, Turkey
Abstract :
The prevalence of autoimmune thyroid disease (AITD) has progressively increased. Circulating autoantibodies associated with AITD may affect the result of laboratory analyses and cause incorrect conclusions in the assessment of thyroid hormone status. In this report, we present a patient with Hashimoto’s thyroiditis with high thyrotrophin and free thyroxine (T4) and triiodothyronine (T3) levels due to the presence of auto-antibodies to iodothyronines. Free T4 and free T3 levels measured by direct immunometric assays method were high, while those estimated by measurement of the serum T4-binding capacity were low. L-thyroxine replacement therapy was started. In patients with discrepant laboratory results, interference from autoantibodies should be considered
NaturalLanguageKeyword :
Thyroxine auto , antibody , hypothyroidism , false high free thyroxine , triiodothyronine levels
