Author/Authors :
DURAL, Özlem Istanbul University - Faculty of Medicine - Department of Obstetrics and Gynecology, Turkey , YAŞA, Cenk Istanbul University - Faculty of Medicine - Department of Obstetrics and Gynecology, Turkey , ACAR, Deniz K. Kanuni Sultan Suleyman Training and Research Hospital - Department of Maternal and Fetal Medicine, Turkey , YILDIRIM, Gökhan Kanuni Sultan Suleyman Training and Research Hospital - Department of Maternal and Fetal Medicine, Turkey , BESTEL, Melih Kanuni Sultan Suleyman Training and Research Hospital - Department of Maternal and Fetal Medicine, Turkey , TEKELİ, Sedat Kanuni Sultan Suleyman Training and Research Hospital - Department of Maternal and Fetal Medicine, Turkey , ASLAN, Halil Kanuni Sultan Suleyman Training and Research Hospital - Department of Maternal and Fetal Medicine, Turkey
Abstract :
Objective: The study was aimed to determine the safety and efficacy of the vaginal administration of low dose misoprostol for late pregnancy termination in women with prior caesarean and unscarred uteri.Study design: A retrospective study was carried out from January 2008 to June 2012 on 209 pregnant women who underwent termination of pregnancy in the second and early third trimester. Among the women, 173 did not have a uterine scar (Group 1) while 36 had a history of prior caesarean (Group 2). The induction-to-abortion interval, the rate of complications and failureand the need for a different method during the process were assessed.Results: In group 1, 145 of patients (83.8%) delivered vaginally in 48 hours, the mean duration of the induction-to-abortion interval was 21±10.3 hours. In this group, 11 patients (6.3%) needed one or more different methods and one case of uterine rupture (0.57%) was observed. In group 2, 26 of patients (72.2%) delivered vaginally in 48 hours (p=0.11), the mean induction-abortion interval was 22.7±10.8 hours (p=0.45). Six patients (16.7%) needed a different method (p=0.05) and there was also one case (2.7%) of ruptured uterus (p=0.28).Conclusion: Administration of low-dose vaginal misoprostol appears to be effective without excessive side effects or complications for late pregnancy termination
