Author/Authors :
ÜLKÜ, Sabiha Zelal Dicle Üniversitesi - Diş Hekimliği Fakültesi - Protetik Diş Tedavisi Anabilim Dalı, Turkey
Abstract :
Osteogenesis imperfecta (OI) or ‘brittle bone disease’ is a rare connective tissue disorder characterized by increased bone fragility and low bone mass. Genetically and fenotipically heterogeneous group of hereditary metabolic disorders. Typically, patients with OI exhibit osseous tissue fragility, dentinogenesis imperfecta, blue sclera, hearing loss, laxity of the joints, excessive perspiration, short length, easy echimose development, cardiopulmoner anomalies. There is very varying degrees in the frequency and severity of the symptoms among patients.We aimed in this article a 18 and 22 years old brothers in a osteogenesis imperfecta case evaluation, brothers were seven years periodically to be followed.
