Author/Authors :
Üstek, Duran Istanbul Üniversitesi - Deneysel Tip Arastirma Enstitüsü - Genetik AD, Turkey , Abaci, Neslihan Istanbul Üniversitesi - Deneysel Tip Arastirma Enstitüsü - Genetik AD, Turkey , Sirma, Sema Istanbul Üniversitesi - Deneysel Tip Arastirma Enstitüsü - Genetik AD, Turkey , Çakiris, Aris Istanbul Üniversitesi - Deneysel Tip Arastirma Enstitüsü - Genetik AD, Turkey
Title Of Article :
New Generation DNA Sequencing
Abstract :
Next-generation sequencing has a potential to dramatically accelerate biological research, by enabling the comprehensive analysis of genomes, transcriptomes and DNA-protein interactions to become inexpensive, routine and widespread. The next-generation sequencing technologies offer novel and rapid ways for genome-wide characterisation and profiling of mRNAs, small RNAs, transcription factor binding regions, structure of chromatin and DNA methylation patterns, ancient DNA, microbiology and metagenomics. This review discusses next generation sequencing technologies, recent advances in next generation sequencing systems and applications for next generation technologies.
JournalTitle :
Deneysel Tıp Araştırma Enstitüsü Dergisidir