Author/Authors :
Gelmez, Metin Yusuf Istanbul üniversitesi - Deneysel Tip Arastirma Enstitüsü - Immünoloji Anabilim Dali, Turkey , Kasapoglu, Pinar Istanbul üniversitesi - Deneysel Tip Arastirma Enstitüsü - Immünoloji Anabilim Dali, Turkey , Adas, Çagdas Ugur Istanbul üniversitesi - Deneysel Tip Arastirma Enstitüsü - Immünoloji Anabilim Dali, Turkey , Tahrali, Ilhan Istanbul üniversitesi - Deneysel Tip Arastirma Enstitüsü - Immünoloji Anabilim Dali, Turkey , Gazioglu, Sema Bilgiç Istanbul Üniversitesi - Deneysel Tip Arastirma Enstitüsü (DETAE) - Immünoloji Anabilim Dali, Turkey , Çevik, Aydin Deneysel Tip Arastirma Enstitüsü - Deneysel Tip Arastirma Enstitüsü - Deney Hayvanlari Biyolojisi ve Biyomedikal Uygulama Teknikleri Anabilim Dali, Turkey , Deniz, Günnur Istanbul Üniversitesi - Deneysel Tip Arastirma Enstitüsü (DETAE) - Immünoloji Anabilim Dali, Turkey
Abstract :
One of the common health problems seen with increasing frequency in today s modern societies, the metabolic syndrome (MS), occurs with co-development of insulin resistance, obesity, dyslipidemia and hypertension problems. Environmental factors, sedentary lifestyle and unhealthy diet together with a genetic predisposition also play a role in the emergence of the disease. Many diseases such as cardiovascular diseases, fatty liver, polycystic ovary syndrome may occur as a result of the metabolic syndrome development. Research is being done throughout the world and experimental animal models are commonly utilized for this purpose. Mouse, rat, New Guinea pig, hamster and sheep are the most preferred experimental animal species in research of metabolic syndrome. Genetically obese/diabetic and/or diet induced obesity/diabetes diseases models have been used in this animal models. This review aims to give general information about metabolic syndrome and experimental animal studies which are often used in metabolic syndrome studies, additionally.
