Söker, Sevda Dicle Üniversitesi - Tıp Fakültesi - Histoloji ve Embriyoloji AD, Turkey , Çakmak, Sevin Dicle Üniversitesi - Tıp Fakültesi - Göz Hastalıkları AD, Turkey , Akkuş, Murat Dicle Üniversitesi - Tıp Fakültesi - Histoloji ve Embriyoloji AD, Turkey , Nergiz, Yusuf Dicle Üniversitesi - Tıp Fakültesi - Histoloji ve Embriyoloji AD, Turkey

Histological evaluation of levator palpebralis superior muscle in patients with congenital blepharoptosis

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Objectives: The aim of this study was to examine levatorpalpebralis superior muscle histologically in patients with congenital blepharoptosis and to investigate the relationship between these findings and age, sex and degree of blefaroptosis in this patient group. Materials and methods: Levator muscle of 13 patients with congenital ptosis, who had applied to Dicle University Medical Faculty Ophthalmology Clinic and had undergone levator palpebralis superior muscle resection between january 2009-january 2010, has been examined histopathologically in Histology and Embriology Deparment. During preoperative period, ptosis amount, levator function (LF), tear functions, Bell’s phenomenon and jaw-winking phenomenon were evaluated. All patients underwent resection of levator palpebralis superior muscle. Received postoperative levator muscle was examined by light microscopy. Results: The average age of 9 (69.2%) male and 4 (30.8%) female cases were 10.61 ± 4.77 (4- 19) years. In histological examination, the quality and quantity of the levator muscle fibrils have been assessed. There was no relationship detected between histological features of levator palpebralis superior muscle and patient’s age and gender (p 0.05). Patients with weak levator palpebralis superior muscle were detected to have fatty degeneration histologically. The higher the levator palpebralis superior muscle function revealed decreased fatty degeneration and increased skeletal muscle fibrils. Conclusion: More ultrastructural studies in larger populations are needed to support the relationship between structure and function of levator palpebralis superior muscle in patients with congenital blepharoptosis.

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Congenital Blepharoptosis , eye , levator muscle , histology

Dicle Medical Journal

69