Author/Authors :
Okyay, Gülay Ulusal Dıskapı Yıldırım Beyazıt Education and Research Hospital - Department of Internal Medicine, Turkey , Yenigün, Ezgi Coşkun Dıskapı Yıldırım Beyazıt Education and Research Hospital - Department of Internal Medicine, Turkey , Pirpir, Atakan Dıskapı Yıldırım Beyazıt Education and Research Hospital - Department of Internal Medicine, Turkey , Ersoy, Osman Hacettepe University - Faculty of Medicine - Department of Internal Medicine-Gastroenterology Division, TURKEY , Yıldırım, İ. Safa Dıskapı Yıldırım Beyazıt Education and Research Hospital - Department of Internal Medicine, Turkey
Abstract :
Hepatic encephalopathy (HE) is a neuropsychiatric syndrome of patients with chronic liver disease. In addition to ammonia levels, increased manganese levels in the brain are also considered as having role in the pathogenesis of HE. On cranial T1-weighted magnetic resonance imaging (MRI), hyperintense and symmetrical globus pallidi linked to the manganese deposition are characteristic for patients with cirrhosis of the liver. We presented here a case of portal-systemic encephalopathy demonstrated with typical MR images and increased blood manganese concentration.
NaturalLanguageKeyword :
Chronic liver disease , manganese , T1 , weighted hyperintensity
