مرکز منطقه ای اطلاع رساني علوم و فناوري - The relationships between waist circumference as an indicator of central obesity and lower urinary tract symptoms, erectile dysfunction and metabolic syndrome components

Abstract :

Objectives: In this study, we aimed to evaluate the relationship between waist circumference, which is as an indicator of central obesity, and lower urinary tract symptoms, erectile dysfunction and metabolic syndrome components. Materials and methods: The data of 52 patients with moderate-severe lower urinary tract symptoms, who had no previous diagnosis of benign prostatic hyperplasia and prostate specific antigen 4 ng/ml were retrospectively analyzed. The patients were divided in 3 subgroups according to the waist circumference ( 94 cm, 94-102 cm, 102 cm). Age, weight, urine flow rates, prostate volume, and prostate specific antigen value and lipid profiles were separately determined for all patients. Data on chronic systemic diseases and erectile function was also evaluated and possible relations between them were investigated. Results: The mean age of patients was 60,6±7,8 years. It was determined that diabetes in 17 (%32,69), hypertension in 22 (%42,30), coronary artery disease in 13 (%25) and erectile dysfunction in 24 (%46.15) patients. Positive correlations were found between waist circumference and the parameters of age, International Prostate Symptom Score, body weight, prostate volume, triglyceride and LDL-cholesterol levels. Nevertheless, there was a negative correlation between waist circumference and urine flow rates. While the data of all subgroups were compared, it was seen that increased waist circumference was with worsened lower urinary tract symptoms and sexual function. Conclusions: Increased waist circumference had negative impacts on lower urinary tract symptoms and sexual functions, and it was with increasing frequency of diabetes, coronary heart disease, hypertension and metabolic syndrome.