Author/Authors :
Aydın, Banu Dr Sami Ulus Maternity and Children Research and Training Hospital - Department of Neonatology, Turkey , Dilli, Dilek Dr Sami Ulus Maternity and Children Research and Training Hospital - Department of Neonatology, Turkey , Zenciroğlu, Ayşegül Dr. Sami Ulus Maternity and Children’s Hospital - Department of Neonatology, Turkey , Erdoğan, Derya Dr. Sami Ulus Maternity and Children’s Hospital - Department of Pediatric Surgery, Turkey , Karaman, İbrahim Sami Ulus Maternity and Children s Hospital - Department of Pediatric Surgery, Turkey , İpek, Mehmet Şah Dr. Sami Ulus Maternity and Children’s Hospital - Department of Neonatology, Turkey , Okumuş, Nurullah Dr. Sami Ulus Maternity and Children’s Hospital - Department of Neonatology, Turkey
Abstract :
Prostaglandin E1 infusion is widely used to maintain patency of ductus arteriosus in newborns with duct-dependent congenital heart disease until surgery. Prostaglandin E1 is a lifesaving drug, but it has many side effects including fever, apnea, bradycardia, hypotension, convulsion, edema, and cortical hyperostosis. The gastrointestinal tract has not been recognized as a major site of serious adverse effects of prostaglandin E1 infusion, although diarrhea is a well-recognized side effect that usually responds to dose reduction. In this report, we present a case of intestinal intussusception presumably induced by prostaglandin therapy in a newborn with duct-dependent congenital heart disease.
