Author/Authors :
Ertürk, Mehmet Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Surgit, Özgür Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Yalcın, Ahmet Arif Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Uzun, Fatih Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Akgül, Özgür Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Gürdoğan, Muhammet Private Keşan Hospital - Cardiology Clinic, Turkey , Aktürk, İbrahim Faruk Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Öner, Ender Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Birant, Ali Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey , Eksik, Abdurrahman Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital - Department of Cardiology, Turkey
Abstract :
Objective: The aim of this study was to investigate the correlations between leukocyte counts, the neutrophil-to-lymphocyte ratio (NLR), and slow coronary flow (SCF). Methods: We evaluated 135 patients undergoing coronary angiography (CAG) within coronary artery disease (CAD) indication. We divided patients into three groups according to the CAG findings. Group 1 consisted of 45 patients with an SCF pattern; group 2 consisted of 45 patients with at least 50% lumen narrowing in at least one epicardial coronary artery; and group 3 (control group) consisted of 45 patients with normal coronary arteries. The quantification of the coronary flow was assessed using the thrombolysis in myocardial infarction (TIMI) frame count method for each of the coronary arteries. Blood samples were collected from the patients after a 12 h overnight fasting. The NLR ratio was calculated from the automated complete blood count. Results: NLR in CAD was higher than in both the SCF and control groups (p=0.008, p 0.001, respectively). However, there was no statistically significant difference between SCF and control group (p=0.768). Neutrophil counts in CAD were higher than in both SCF and control groups, but only the difference between CAD and SCF groups was statistically significant (p=0.010). Conclusion: Our study revealed that circulating neutrophil counts and NLR were related to the coronary artery disease, as expected.
NaturalLanguageKeyword :
Neutrophil , to , lymphocyte ratio , leukocyte subtype , slow coronary flow , coronary artery disease
