Author/Authors
Yazmalar, Levent Dicle University - Faculty of Medicine - Dept Physical Medicine and Rehabilitation, Turkey , Batmaz, İbrahim Dicle Üniversitesi - Tıp Fakültesi - Fizik Tedavi ve Rehabilitasyon Anabilim Dalı, Turkey , Dağlı, Zübeyr Dicle Üniversitesi - Tıp Fakültesi - Fiziksel Tıp ve Rehabilitasyon Ana Bilim Dalı, Türkiye , Hattapoğlu, Erkam Dicle Üniversitesi - Tıp Fakültesi - Fiziksel Tıp ve Rehabilitasyon Ana Bilim Dalı, Türkiye , Sarıyıldız, Mustafa Akif Dicle University - Faculty of Medicine - Dept Physical Medicine and Rehabilitation, Turkey
Title Of Article
Zoledronic acid treatment in an adult patient with Osteogenesis Imperfecta: A case report and review of the literature
شماره ركورد
27015
Abstract
Osteogenesis Imperfecta (OI) is a rare heritable condition characterized by bone fragility and reduced bone mass. This pathology is characterized by disruption of biosynthesis of Type I collagen, and production of limited amount of defective and imperfect collagens. This causes decrease in bone mass of human body, bones become fragile and brittle, resulting in unreasonable multiple fractures. Other manifestations include hyperextensibility of the joints, blue sclera, hearing loss, short stature and dentinogenesis imperfecta. Bisphosphonates are now the most widely used for the treatment of OI. In conclusion, along with the literature, we present a case of zoledronic acid treatment in adult patient with OI.
From Page
425
NaturalLanguageKeyword
Osteogenesis imperfecta , osteoporosis , zoledronic acid
JournalTitle
Dicle Medical Journal
To Page
428
JournalTitle
Dicle Medical Journal
Link To Document