Baygutalp, Nurcan Kılıç Ataturk University - Faculty of Medicine - Department of Medical Biochemistry, Turkey , Baygutalp, Fatih Ataturk University - Faculty of Medicine - Department of Physical Medicine and Rehabilitation, Turkey , Şeferoğlu, Buminhan Ataturk University - Faculty of Medicine - Department of Physical Medicine and Rehabilitation, Turkey , Bakan, EEbubekir Ataturk University - Faculty of Medicine - Department of Medical Biochemistry, Turkey

The relation between serum vitamin D levels and clinical findings of fibromyalgia syndrome

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Objective: This study was performed to identify serum 25-OH vitamin D levels and to investigate the relationship between 25-OH vitamin D and clinical findings on patients with fibromyalgia syndrome (FMS). Methods: Nineteen premenopausal women with FMS who were diagnosed according to ACR 1990 fibromyalgia diagnostic criteria and 24 premenopausal healthy women as control group were included in the study. Serum 25-OH vitamin D levels were determined in both patient and control groups. Widespread body pain, headache, fatigue, morning stiffness, sleep disorder, the number of tender points, Fibromyalgia Impact Questionnaire (FIQ) scores and Beck depression scores were evaluated as clinical findings in patients with FMS. Results: Serum 25-OH vitamin D levels were significantly lower in patients with FMS than those in control group (p=0.01). There were significantly negative correlations between 25-OH vitamin D levels and widespread body pain (r=-0.731), Beck depression scores (r=-0.777), headache (r=-0.629), and sleep disorder (r=-0.767) in the FMS group (p 0.01). Conclusion: It was concluded that 25-OH vitamin D deficiency may be related to the clinical findings such as widespread body pain, depression, headache and sleep disorder in patients with FMS.

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Fibromyalgia , clinical finding , 25 , OH vitamin D

Dicle Medical Journal

450