Başyigit, Sebahat Artvin State Hospital - Department of Gastroenterology, Turkey , Asiltürk, Zeliha Keçioren Research and Training Hospital - Department of Internal Medicine, Turkey , Sapmaz, Ferdane Keçioren Research and Training Hospital - Department of Gastroenterology, Turkey , Kefeli, Ayşe Siirt State Hospital - Department of Gastroenterology, Turkey , Yeniova, Abdullah Özgür Gaziosmanpaşa University - Faculty of Medicine - Department of Gastroenterology, Turkey , Uzman, Metin Keçioren Research and Training Hospital - Department of Gastroenterology, Turkey , Nazligul, Yaşar Keçioren Research and Training Hospital - Department of Gastroenterology, Turkey

Hepatitis B virus is still the most common etiologic factor of liver cirrhosis: Results from a single center in Turkey

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Objective: It is important to examine the epidemiology of liver cirrhosis (LC) because of it is a preventable disease. In this single-center study, we aimed to determine the epidemiological characteristics and etiology of LC in Central Anatolian region of Turkey.Methods: We reviewed data of patients with liver cirrhosis who presented to outpatient and inpatient clinics of our medical center between January 1, 2011 and September 31, 2014Results: Overall, 135 patients were included to the study: 91 men (67.4%) and 44 women (33%) with a mean age of 63±14,3 years (range: 15–87years). The primary causes of cirrhosis were chronic hepatitis B (CHB) (n: 52, 38.5%) and cryptogenic cirrhosis (n: 33, 24.4%). CHB was the main etiology of cirrhosis in men (49.5%) and cryptogenic LC was predominant in women (40.9%). Patients with alcoholic cirrhosis were solely male. Percentage of patients with autoimmune hepatitis was significantly higher among women (70%). The percentage of patients with HBV was similar between patients aged 50 and 50 years (31.6% and 39.7%, respectively), but percentage of patients with hepatitis C virus was lower (5.3%) in patients aged 50 years when compared to those aged 50 years (14.7%). There was no cirrhotic patients under 50 years of age due to a genetic disorderConclusion: Despite national vaccination program, effective treatment regimens and intensive screening methods against hepatitis B virus, it remains to be the most common cause of LC in our country.

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Viral hepatitis , alcohol induced liver disease , autoimmune hepatitis , cryptogenic liver cirrhosis , non , alcoholic fatty liver disease

Dicle Medical Journal

421