• Author/Authors

    TAKTAK, Fulya Uşak University - Engineering Faculty - Department of Chemical Engineering, Turkey

  • Title Of Article

    Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery

  • شماره ركورد
    27774
  • Abstract
    In this study, poly(2‐dimethylamino)ethyl methacrylate (PDMAEMA) gels were prepared via in situpolymerization reaction. Synthesized hydrogel was characterized with FTIR spectroscopy and SEM. The pH‐ and temperature dependent swelling / deswelling behavior was investigated. The hydrogel showed highest value of swelling at pH 2. The rising temperature led to a decrease in swelling ratio due to the fact that hydrophobic interactions between polymer segments become dominant. Furthermore, it was observed that PDMAEMA hydrogel exhibited rapid deswelling rate in response to temperature and pH. The drug release profile of PDMAEMA hydrogel has been reported by using Ibuprofen as a model drug.
  • From Page
    68
  • NaturalLanguageKeyword
    Hydrogel , Controlled drug delivery , Rapid response , Deswelling
  • JournalTitle
    Afyon Kocatepe University Journal Of Science an‎d Engineering
  • To Page
    75
  • JournalTitle
    Afyon Kocatepe University Journal Of Science an‎d Engineering
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=44&DC=27774