Bouasla, Souad Université de Guelma - Faculty of Mathematics, Informatics and materials sciences - Applied chemistry laboratory (ACL), Departmentof materials sciences, Algeria , Teguiche, Mabrouk Université de Guelma - Faculty of Mathematics, Informatics and materials sciences - Departmentof materials sciences, Applied chemistry laboratory (ACL), Algeria

MULTICOMPONENT SYNTHESIS OF 1, 4-DISUBSTITUTED 1,2,3-TRIAZOLES VIA CU(I)CATALYZED REACTION

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1,4-disubstituted 1,2,3-triazoles are obtained in high yields via one-pot three components reaction (TCC), coupling alkyl bromide , sodium azide and phenylacetylene and catalyzed by Cu I (10%), under ultrasonic irradiations at room temperature. The use of water as a medium’’green solvent’’ makes this process safe, economic and environmental friendly (green chemistry).

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alkyl bromide , phenylacetylene , TCC , green chemistry , sonochemistry , 1 , 2 , 3 , triazole , CuI

Journal Marocain De Chimie Hétérocyclique

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