Author/Authors :
Ouchbani, T. Mohammed-V University Agdal - Laboratoire de Chimie Organique Hétérocyclique, Morocco , Ouchbani, T. Heinrich Heine University Düsseldorf - Institut für Pharmazeutische Biologie und Biotechnologie, Germany , Janati Idrissi, F. E. Mohammed-V University Agdal - Laboratoire d’Electrochimie et Chimie Analytique, Maroc , Janati Idrissi, F. E. Heinrich Heine University Düsseldorf - Institut für Pharmazeutische Biologie und Biotechnologie, Germany , Bouhfid, R. École Normale Supérieure de l Enseignement Technique-ENSET - Moroccan Foundation Advanced Science, Innovation and Research (MAScIR), Institute of Nanomaterials and Nanotechnology (INANOTECH), Morocco , Proksch, P. Heinrich Heine University Düsseldorf - Institut für Pharmazeutische Biologie und Biotechnologie, Germany , Essassi, E. M. Université Mohammed V - Agdal - Faculté des Sciences - Laboratoire de Chimie Organique Hétérocyclique, Maroc , Essassi, E. M. École Normale Supérieure de l Enseignement Technique-ENSET - Moroccan Foundation Advanced Science, Innovation and Research (MAScIR), Institute of Nanomaterials and Nanotechnology (INANOTECH), Morocco
Title Of Article :
NEONECTRIA MACRODIDYMA AND EMBELLISIA EUREKA, TWO NOVEL PRODUCERS OF BREFELDIN A AND 3, 4-DIHYDRO-3,4,8-TRIHYDROXY-1[2H]-NAPHTHALENONE
Abstract :
In the present investigation, we worked on isolation and elucidation of endophytic fungi secondary metabolites. We were interested by isolation of two endophytic fungi, Embellisia eureka and Neonectria macrodidyma as new producers of Brefeldin A and 3,4-dihydro-3,4,8-trihydroxy-1[2H]-naphthalenone. The fungi were isolated from two Moroccan plant species, respectively are Mentha pulegium and Cladanthus Arabicus. From embellisia we isolated the 3,4,8- trihydroxy-1[2H]-naphthalenone and from the second fungi we isolated the Brefeldin A. The characterization and structure elucidation were done by using chromatography technics, high resolution mass spectrometry (HRMS), mass spectrometry LC-MS/MS, NMR and crystal diffraction X-Ray (DRX) analysis.
NaturalLanguageKeyword :
Embellisia eureka , Neonectria macrodidyma , NMR , HRMS , MS , MS , DRX , brefeldin A , naphtalenone
JournalTitle :
Journal Marocain De Chimie Hétérocyclique
