meskini, i. université sidi mohammed ben abdellah - laboratoire de chimie organique, Fès, Morocco , daoudi, m. université sidi mohammed ben abdellah - laboratoire de chimie organique, Fès, Morocco , kerbal, a. université sidi mohammed ben abdellah - laboratoire de chimie organique, Fès, Morocco , daran, j.-c. laboratoire de chimie de coordination, 205 route de narbonne, toulouse cedex, France , zouihri, hafid centre national pour la recherche scientifique et technique, uatrs, Rabat, Morocco , chohan, z. h. bahauddin zakariya university - department of chemistry, Multan, Pakistan , ben hadda, t. université mohammed premier - laboratoire chimie matériaux, Oujda, Morocco

CRYSTAL STRUCTURE OF NEW ANTI-HIV CANDIDATE: [(4-BROMO-3,5-DIMETHYL-PYRAZOL-1-YL)(4-CHLOROPHENYL)- METHYL]-PROPANEDIOATE

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The titled new functionalized N,O,O- donor ligand, [(4-bromo-3,5-dimethylpyrazol-1-yl)(4-chlorophenyl)-methyl]-propanedioate (4) is prepared in good yield throughcondensation of 4-bromo-3,5-dimethyl pyrazole, with 2-arylidene-malonic acid diethyl esters(3). The structure of compound (4) was determined by spectral (IR, 1H NMR), elementalanalyses and X-ray diffraction data. The molecular conformation shows two possible pocketsready to coordinate with two metal atoms.

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N , O , O donor ligand , b , amino dicarbonyl , malonate , Michael reaction

Journal Marocain De Chimie Hétérocyclique

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